FKBP51F67V-selective antagonist Ligand2
Ligand2 (example 3-3) is a potent and selective antagonist for the FKBP51 F67V mutant, exhibiting no binding to wild-type FKBP51 or FKBP52. It has been shown in research to reverse anxiety-related behaviors in vivo following amygdala-specific overexpression of the F67V variant, supporting its use in neuropsychiatric and stress-related studies.
Product Specifications
CAS Number
1680228-76-5
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
[C@H] (C (=O) N1[C@H] (C (O[C@H] (CCC2=CC (OC) =C (OC) C=C2) C3=CC (OCCN4CCOCC4) =CC=C3) =O) CCCC1) (CC=C) C5=CC (OC) =C (OC) C (OC) =C5
Molecular Formula
C43H56N2O10
Molecular Weight
760.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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