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S-Gem

S-Gem is a thioredoxin reductase (TrxR) -activated prodrug of Gemcitabine designed for targeted cytotoxicity. It demonstrates reduced off-target toxicity compared to the parent compound, making it a useful research tool for studying redox biology and prodrug strategies in cancer models, both in vitro and in vivo.

Product Specifications

CAS Number

2169925-98-6

Field of Research

Cell Biology, Molecular Biology

Smiles

FC1 (F) [C@@H] (O[C@H] (CO) [C@H]1O) N2C (=O) N=C (NC (OC3CSSC3) =O) C=C2

Molecular Formula

C13H15F2N3O6S2

Molecular Weight

411.4

Storage Conditions

-20°C

Notes

For research use only.

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