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AZD4747

AZD4747 is a brain-penetrant, selective inhibitor of the KRASG12C mutant protein. It is utilized in preclinical oncology research, particularly for studying pancreatic and colorectal cancers, with demonstrated activity in both cellular assays and in vivo tumor models.

Product Specifications

CAS Number

2489226-14-2

Product Name Alternative

KRAS G12C

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Purity

99.36% (May vary between batches)

Solubility

DMSO:100 mg/mL (226.81 mM)

Smiles

O=C (C=C) N1CCN2CC3=CC (C#CC) =C (C (F) =C3OCC2C1) C=4C (Cl) =CC=CC4O

Molecular Formula

C24H22ClFN2O3

Molecular Weight

440.89

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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