AZD4747
AZD4747 is a brain-penetrant, selective inhibitor of the KRASG12C mutant protein. It is utilized in preclinical oncology research, particularly for studying pancreatic and colorectal cancers, with demonstrated activity in both cellular assays and in vivo tumor models.
Product Specifications
CAS Number
2489226-14-2
Product Name Alternative
KRAS G12C
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.36% (May vary between batches)
Solubility
DMSO:100 mg/mL (226.81 mM)
Smiles
O=C (C=C) N1CCN2CC3=CC (C#CC) =C (C (F) =C3OCC2C1) C=4C (Cl) =CC=CC4O
Molecular Formula
C24H22ClFN2O3
Molecular Weight
440.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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