HIV-1 protease-IN-9
HIV-1 protease-IN-9 (compound 5b) is a highly potent small molecule inhibitor of HIV-1 protease, demonstrating sub-nanomolar binding affinity (K_i = 0.028 nM) and effective antiviral activity (IC_50 = 66.8 nM) . This inhibitor is a valuable research tool for in vitro antiviral assays and mechanistic studies of protease function in HIV replication.
Product Specifications
CAS Number
2925381-27-5
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Smiles
N (C=1N=C (C=CN1) C=2C=CC=NC2) C3=CC (C (N[C@H] ([C@@H] (CN (S (=O) (=O) C4=CC=C (N) C=C4) CC (C) C) O) CC5=CC=CC=C5) =O) =CC=C3C
Molecular Formula
C37H41N7O4S
Molecular Weight
679.83
Storage Conditions
-20°C
Notes
For research use only.
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