IRAK4-IN-28
IRAK4-IN-28 (compound 42) is a potent, orally bioavailable IRAK4 inhibitor with an IC50 of 8.9 nM and a Kd of 0.58 nM. This research compound is used to investigate IRAK4 signaling in preclinical models of inflammatory and autoimmune disorders, both in vitro and in vivo.
Product Specifications
CAS Number
2952532-92-0
Field of Research
Immunology & Inflammation, Signal Transduction
Smiles
C (NC=1N=C (C=CC1) C=2C=NN (C) C2) (=O) C3=C (N=C4C (=C3) OC (=N4) N5CCOCC5) N6CCN (CC6) C7CC7
Molecular Formula
C27H31N9O3
Molecular Weight
529.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
A04026-2-HRP 100 µg/Vial
Anti-BOP1 Antibody Picoband® HRP Conjugated
Sign In for Pricing
View Details A02419-4-Biotin 100 µg/Vial
Anti-Alpha 1 microglobulin/Ambp Antibody Picoband® (Biotine Conjugate)
Sign In for Pricing
View Details