IRAK4-IN-28
IRAK4-IN-28 (compound 42) is a potent, orally bioavailable IRAK4 inhibitor with an IC50 of 8.9 nM and a Kd of 0.58 nM. This research compound is used to investigate IRAK4 signaling in preclinical models of inflammatory and autoimmune disorders, both in vitro and in vivo.
Product Specifications
CAS Number
2952532-92-0
Field of Research
Immunology & Inflammation, Signal Transduction
Smiles
C (NC=1N=C (C=CC1) C=2C=NN (C) C2) (=O) C3=C (N=C4C (=C3) OC (=N4) N5CCOCC5) N6CCN (CC6) C7CC7
Molecular Formula
C27H31N9O3
Molecular Weight
529.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rat Monoclonal TCF7/TCF1 Antibody (812145) [DyLight 650]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
FAB8224W 0.1 mL
Rat Monoclonal TCF7/TCF1 Antibody (812145) [DyLight 650]
Sign In for Pricing
View Details 
32265126 3x 1.0µg DNA
NUCB1 CRISPRa sgRNA lentivector (set of three targets)(Rat)
Sign In for Pricing
View Details MBS1187401-01 1 mg (E-Coli)
Recombinant Salmonella paratyphi C Na (+)/H (+) antiporter nhaB, partial
Sign In for Pricing
View Details MBS1187401-02 1 mg (Yeast)
Recombinant Salmonella paratyphi C Na (+)/H (+) antiporter nhaB, partial
Sign In for Pricing
View Details