IRAK4-IN-28
IRAK4-IN-28 (compound 42) is a potent, orally bioavailable IRAK4 inhibitor with an IC50 of 8.9 nM and a Kd of 0.58 nM. This research compound is used to investigate IRAK4 signaling in preclinical models of inflammatory and autoimmune disorders, both in vitro and in vivo.
Product Specifications
CAS Number
2952532-92-0
Field of Research
Immunology & Inflammation, Signal Transduction
Smiles
C (NC=1N=C (C=CC1) C=2C=NN (C) C2) (=O) C3=C (N=C4C (=C3) OC (=N4) N5CCOCC5) N6CCN (CC6) C7CC7
Molecular Formula
C27H31N9O3
Molecular Weight
529.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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