Anticancer agent 147
Compound 6j (Anticancer agent 147) is a sophoridine-derived ferroptosis inducer with potent activity against liver cancer. It exerts its effects by promoting Fe2+, ROS, and MDA accumulation, enhancing ER stress, and upregulating ATF3, as demonstrated in both cellular and animal studies.
Product Specifications
CAS Number
2241283-11-2
Field of Research
Cell Biology
Smiles
C (CCC (OC) =O) [C@@H]1[C@@]2 ([C@@]3 ([C@@] (CN1CC=4C=5C (N (CC6=CC=C (Br) C=C6) C4) =CC=CC5) (CCCN3CCC2) [H]) [H]) [H]
Molecular Formula
C32H40BrN3O2
Molecular Weight
578.58
Storage Conditions
-20°C
Notes
For research use only.
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