BLT2 antagonist-1
BLT2 antagonist-1 (compound 15b) is a selective BLT2 receptor inhibitor with a K_i of 132 nM, blocking LTB4 binding and inhibiting BLT2-mediated chemotaxis (IC50 224 nM) without affecting BLT1. It serves as a valuable research tool for studying the role of BLT2 in inflammatory airway disease models such as asthma and COPD.
Product Specifications
CAS Number
2069220-61-5
Field of Research
Pharmacology & Drug Discovery
Smiles
N (CC1=CC=C (C=C1) C2=CC=C (OCC (O) =O) C=C2) (C (CCCC) =O) C3=CC (F) =CC=C3
Molecular Formula
C26H26FNO4
Molecular Weight
435.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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