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BLT2 antagonist-1

BLT2 antagonist-1 (compound 15b) is a selective BLT2 receptor inhibitor with a K_i of 132 nM, blocking LTB4 binding and inhibiting BLT2-mediated chemotaxis (IC50 224 nM) without affecting BLT1. It serves as a valuable research tool for studying the role of BLT2 in inflammatory airway disease models such as asthma and COPD.

Product Specifications

CAS Number

2069220-61-5

Field of Research

Pharmacology & Drug Discovery

Smiles

N (CC1=CC=C (C=C1) C2=CC=C (OCC (O) =O) C=C2) (C (CCCC) =O) C3=CC (F) =CC=C3

Molecular Formula

C26H26FNO4

Molecular Weight

435.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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