RDN2150
RDN2150 (Compound 25) is a potent and covalent ZAP-70 inhibitor (IC50=14.6 nM) targeting C346. It suppresses CD25/CD69 expression and CD4+ T cell activation, supporting its application in immunology and autoimmune disease research, such as psoriasis, in both in vitro and in vivo studies.
Product Specifications
CAS Number
2839429-51-3
Field of Research
Protein Biochemistry
Smiles
O=C (C=C) NC1=CC (=CC=C1Cl) CNC2=NC (NC3=CC=C (C (OC) =C3) N4CCOCC4) =C (C (=O) N) C5=NC=CN25
Molecular Formula
C28H29ClN8O4
Molecular Weight
577.03
Storage Conditions
-20°C
Notes
For research use only.
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