PROTAC SMARCA2 degrader-2
PROTAC SMARCA2 degrader-2 is a potent and selective degrader of SMARCA2/4, demonstrating high cellular potency (IC50 <0.1 μM) . This tool compound is valuable for in vitro and in vivo research on SMARCA4-deficient cancers, such as certain lung and ovarian malignancies.
Product Specifications
CAS Number
2892523-74-7
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
C (N1CCC2 (NC=3C (NC2) =NN=C (C3) C4=C (O) C=CC=C4) CC1) C5CCN (CCOC=6C=C ([C@H] (C (=O) N7[C@H] (C (N[C@@H] (C) C8=CC=C (C=C8) C9=C (C) N=CS9) =O) C[C@@H] (O) C7) C (C) C) ON6) CC5
Molecular Formula
C49H62N10O6S
Molecular Weight
919.15
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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