PROTAC BRD4 Degrader-22

PROTAC BRD4 Degrader-22 (Compound 44h) is a heterobifunctional degrader that potently targets the BRD4 protein, demonstrating a pDC50 of 9.2 in MOLT4 leukemia cells after 24-hour treatment. This tool compound is widely used in vitro to study BRD4's role in oncology and transcriptional regulation, facilitating the exploration of targeted protein degradation as a therapeutic strategy.