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PonatiLink-1-24

Ponatinib (PonatiLink-1-24) is a potent and selective ABL tyrosine kinase inhibitor. It is widely used in biochemical and cellular research to study BCR-ABL-driven leukemias, including in vitro assays and in vivo xenograft models for investigating resistance mechanisms.

Product Specifications

CAS Number

2941512-45-2

Field of Research

Cardiovascular Research, Signal Transduction

Smiles

O=C (NC1=CC=C (OC (F) (F) Cl) C=C1) C=2C=NC (=C (C2) C3=NNC=C3) N4CCC (C (=O) NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC (=O) N5CCN (CC6=CC=C (C=C6C (F) (F) F) NC (=O) C7=CC=C (C (C#CC8=CN=C9C=CC=NN89) =C7) C) CC5) CC4

Molecular Formula

C101H144ClF5N12O29

Molecular Weight

2120.73

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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