Pomalidomide-C5-Dovitinib
Pomalidomide-C5-Dovitinib is a PROTAC degrader for research use, targeting FLT3-ITD and KIT proteins via the ubiquitin-proteasome system. It demonstrates potent in vitro antiproliferative activity in FLT3-ITD+ AML cell models by inhibiting oncogenic signaling pathways.
Product Specifications
CAS Number
2732969-67-2
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1NC=2C=CC=C (F) C2C (N) =C1C3=NC4=CC=C (C=C4N3) N5CCN (C (=O) CCCCCNC6=CC=CC=7C (=O) N (C (=O) C67) C8C (=O) NC (=O) CC8) CC5
Molecular Formula
C39H38FN9O6
Molecular Weight
747.77
Storage Conditions
-20°C
Notes
For research use only.
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