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PKM2 activator 6

Compound Z10 is a dual-action small molecule functioning as a PKM2 activator (K_D = 121 μM) and a PDK1 inhibitor (K_D = 19.6 μM) . It suppresses proliferation, migration, and glycolysis while inducing apoptosis in colorectal cancer cell lines such as DLD-1, HCT-8, and HT-29, making it a useful tool for studying cancer metabolism in vitro.

Product Specifications

Field of Research

Metabolism Research, Signal Transduction

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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