PKM2 activator 6
Compound Z10 is a dual-action small molecule functioning as a PKM2 activator (K_D = 121 μM) and a PDK1 inhibitor (K_D = 19.6 μM) . It suppresses proliferation, migration, and glycolysis while inducing apoptosis in colorectal cancer cell lines such as DLD-1, HCT-8, and HT-29, making it a useful tool for studying cancer metabolism in vitro.
Product Specifications
Field of Research
Metabolism Research, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.
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