PI3Kδ-IN-17
PI3Kδ-IN-17 (Compound S5) is a highly potent and selective inhibitor of PI3Kδ, demonstrating an IC50 of 2.82 nM against the enzyme. It effectively inhibits the proliferation of SU-DHL-6 lymphoma cells (IC50 = 0.035 μM), supporting its use in hematological cancer research, both in vitro and in preclinical in vivo models.
Product Specifications
CAS Number
2768181-63-9
Field of Research
Signal Transduction
Smiles
N (C=1C2=C (C=CC (=N2) C=3C=C (C (F) (F) F) C (OC) =NC3) N=CN1) [C@@H]4CN (C (=O) [C@@H]5CCCN5) CC4
Molecular Formula
C23H24F3N7O2
Molecular Weight
487.48
Storage Conditions
-20°C
Notes
For research use only.
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