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PCSK9-IN-20

PCSK9-IN-20 (Compound 3i) is a small molecule inhibitor of PCSK9 with an IC50 of 3.96 μM. It has been demonstrated in vitro to lower PCSK9 levels and subsequently upregulate LDLR protein, making it a useful research tool for studying cholesterol metabolism and potential therapeutic pathways.

Product Specifications

CAS Number

2929219-77-0

Field of Research

Metabolism Research

Smiles

N#CCCNS (=O) (=O) C1=CC=C (C=C1) C (=O) NC2=NC=3C=CC (=CC3S2) CN4CCN (C (=O) OC (C) (C) C) CC4

Molecular Formula

C27H32N6O5S2

Molecular Weight

584.71

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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