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NSC309401 dihydrochloride

NSC309401 is a potent small molecule inhibitor of E. coli dihydrofolate reductase (DHFR), exhibiting an IC50 of 189 nM and a Kd of 14.57 nM. This compound is a valuable research tool for studying bacterial folate metabolism and antibiotic resistance mechanisms in biochemical and microbiological assays.

Product Specifications

CAS Number

77681-42-6

Field of Research

Infectious Disease & Virology

Smiles

NC (C=C1) =CC=C1CN2C=CC3=C4C (N=C (N) N=C4N) =CC=C32.Cl.Cl

Molecular Formula

C17H18Cl2N6

Molecular Weight

377.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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