N3-PEG3-VC-PAB-MMAF
N3-PEG3-VC-PAB-MMAF is a cleavable ADC linker-drug conjugate featuring the cytotoxic payload MMAF and an azide group for bioorthogonal click chemistry conjugation. It is widely used in ADC research for targeted cancer therapy development, enabling the evaluation of drug efficacy in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2757277-32-8
Field of Research
Cell Biology
Smiles
[C@H] ([C@H] (C (N[C@@H] (CC1=CC=CC=C1) C (O) =O) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC3=CC=C (NC ([C@@H] (NC ([C@@H] (NC (COCCOCCOCCN=[N+]=[N-]) =O) [C@H] (C) C) =O) CCCNC (N) =O) =O) C=C3) =O) C) C (C) C) =O) [C@H] (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C66H105N13O17
Molecular Weight
1352.62
Storage Conditions
-20°C
Notes
For research use only.
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