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N3-PEG3-VC-PAB-MMAF

N3-PEG3-VC-PAB-MMAF is a cleavable ADC linker-drug conjugate featuring the cytotoxic payload MMAF and an azide group for bioorthogonal click chemistry conjugation. It is widely used in ADC research for targeted cancer therapy development, enabling the evaluation of drug efficacy in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2757277-32-8

Field of Research

Cell Biology

Smiles

[C@H] ([C@H] (C (N[C@@H] (CC1=CC=CC=C1) C (O) =O) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC3=CC=C (NC ([C@@H] (NC ([C@@H] (NC (COCCOCCOCCN=[N+]=[N-]) =O) [C@H] (C) C) =O) CCCNC (N) =O) =O) C=C3) =O) C) C (C) C) =O) [C@H] (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]

Molecular Formula

C66H105N13O17

Molecular Weight

1352.62

Storage Conditions

-20°C

Notes

For research use only.

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