MS6105
MS6105 is a PROTAC molecule that induces ubiquitin-proteasome-dependent degradation of LDHA and LDHB, demonstrating time-dependent anticancer activity in vitro. Its alkyne handle also enables its use as a click chemistry probe for CuAAC conjugation, facilitating cellular target engagement studies.
Product Specifications
CAS Number
2891709-58-1
Field of Research
Pharmacology & Drug Discovery
Smiles
C (C1=C (CC2CC2) N (N=C1C3=CC (C#CCCCCNC (CCCCCCCCCCCC (N[C@H] (C (=O) N4[C@H] (C (NCC5=CC=C (C=C5) C6=C (C) N=CS6) =O) C[C@@H] (O) C4) C (C) (C) C) =O) =O) =CC=C3) C7=NC (C (O) =O) =CS7) C8=CC=C (S (N) (=O) =O) C=C8
Molecular Formula
C65H81N9O9S3
Molecular Weight
1228.59
Storage Conditions
-20°C
Notes
For research use only.
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