Mp-dLAE-PABC-MMAE
Mp-dLAE-PABC-MMAE is a cleavable linker-payload conjugate for constructing antibody-drug conjugates (ADCs), delivering the cytotoxic agent monomethyl auristatin E (MMAE) . It is widely used in ADC research for targeted cancer therapy, enabling both in vitro cytotoxicity studies and in vivo efficacy assessments in preclinical models.
Product Specifications
CAS Number
2625616-44-4
Smiles
[C@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C1=CC=CC=C1) C) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC3=CC=C (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (NC (CCN4C (=O) C=CC4=O) =O) CC (C) C) =O) C) =O) CCC (O) =O) =O) C=C3) =O) C) C (C) C) =O) [C@@H] (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C68H102N10O17
Molecular Weight
1331.59
Storage Conditions
-20°C
Notes
For research use only.
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