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MMP-7-IN-3

MMP-7-IN-3 (compound 15) is a highly potent and selective matrix metalloproteinase-7 (MMP-7) inhibitor, exhibiting an IC50 of 2.8 nM. This small molecule has demonstrated efficacy in reducing renal fibrosis in a murine unilateral ureteral obstruction model, supporting its use in fibrotic disease research.

Product Specifications

CAS Number

2865097-58-9

Field of Research

Musculoskeletal & Connective Tissue Research, Protein Biochemistry

Purity

99.91% (May vary between batches)

Solubility

DMSO:80 mg/mL (97.77 mM)

Smiles

C ([C@@H] (NC ([C@H] (CC=1C=CN=CC1) NC (CNC (CC[C@H] (NS (=O) (=O) C2=CC (C (F) (F) F) =C (Cl) C=C2) C (O) =O) =O) =O) =O) [C@@] (C) (C) C) (=O) N3[C@H] (CC (N) =O) CCC3

Molecular Formula

C34H43ClF3N7O9S

Molecular Weight

818.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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