METTL3-IN-5
METTL3-IN-5 is a potent and selective METTL3 methyltransferase inhibitor with an IC50 under 2 μM against MOLM-13 AML cells and minimal hERG liability (IC50 >30 μM) . It is a valuable chemical probe for investigating m6A biology and its therapeutic potential in acute myeloid leukemia research, both in vitro and in vivo.
Product Specifications
CAS Number
2965311-25-3
Field of Research
Signal Transduction
Smiles
O=C1C=C (N=C2C=CC=CN12) C (=O) NCC=3SC=4C=C (NC4C3) CNCC56CC (F) (C5) C6
Molecular Formula
C23H22FN5O2S
Molecular Weight
451.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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