MC-VC-PABC-C6-alpha-Amanitin
MC-VC-PABC-C6-alpha-Amanitin is an antibody-drug conjugate (ADC) designed for targeted delivery of the RNA polymerase II inhibitor alpha-Amanitin to HER2-positive cells. It serves as a key research tool for investigating targeted therapies in HER2-overexpressing cancers, such as breast and gastric cancer, in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2922514-69-8
Smiles
O=S1C2=C (C=3C (N2) =CC (OCCCCCCNC (OCC4=CC=C (NC ([C@H] (NC ([C@H] (NC (CCCCCN5C (=O) C=CC5=O) =O) [C@@H] (C) C) =O) CCCNC (N) =O) =O) C=C4) =O) =CC3) C[C@@]6 (NC (=O) [C@] ([C@H] ([C@H] (CO) O) C) (NC (=O) [C@]7 (N (C (=O) [C@H] (CC (N) =O) NC (=O) [C@] (C1) (NC (=O) CNC (=O) [C@] ([C@H] (CC) C) (NC (=O) CNC6=O) [H]) [H]) C[C@H] (O) C7) [H]) [H]) [H]
Molecular Formula
C74H105N17O22S
Molecular Weight
1616.79
Storage Conditions
-20°C
Notes
For research use only.
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