MC-GGFG-AM- (10NH2-11F-Camptothecin)
MC-GGFG-AM- (10NH2-11F-Camptothecin) is a Trop-2-targeting antibody-drug conjugate (ADC) for research use. It employs the sacituzumab antibody connected via a cleavable, pH-sensitive linker to deliver a camptothecin derivative. This construct is applied in oncology research for investigating ADC mechanisms and efficacy in both cellular and animal tumor models.
Product Specifications
CAS Number
2873460-71-8
Smiles
O=C1N2C (C=3C (C2) =CC=4C (N3) =CC (F) =C (NC (CNC ([C@H] (CC5=CC=CC=C5) NC (CNC (CNC (CCCCCN6C (=O) C=CC6=O) =O) =O) =O) =O) =O) C4) =CC7=C1COC (=O) [C@]7 (CC) O
Molecular Formula
C45H45FN8O11
Molecular Weight
892.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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