Mal-PEG8-Phe-Lys-PAB-Exatecan
This ADC features the cleavable Mal-PEG8-Phe-Lys-PAB linker conjugated to the potent topoisomerase I inhibitor Exatecan. It is a research tool for developing targeted cancer therapies and has been utilized in both in vitro cytotoxicity assays and in vivo xenograft model studies.
Product Specifications
CAS Number
2679821-44-2
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Smiles
N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@H] (CC2=CC=CC=C2) NC (CCOCCOCCOCCOCCOCCOCCOCCOCCNC (CCN3C (=O) C=CC3=O) =O) =O) =O) CCCCN) =O) C=C1) =O) [C@@H]4C5=C6C (C=7N (C6) C (=O) C8=C (C7) [C@] (CC) (O) C (=O) OC8) =NC=9C5=C (CC4) C (C) =C (F) C9
Molecular Formula
C73H92FN9O20
Molecular Weight
1434.56
Storage Conditions
-20°C
Notes
For research use only.
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