KY386
KY386 is a potent and selective DHX33 helicase inhibitor (IC50 = 19 nM) with demonstrated anti-cancer activity in DHX33-overexpressing U251-MG glioblastoma cells (IC50 = 20 nM) . It shows moderate metabolic stability and is a useful research tool for investigating DHX33's role in cancer cell proliferation and as a potential therapeutic target in oncology research.
Product Specifications
CAS Number
2787598-01-8
Field of Research
Cell Biology, Molecular Biology
Smiles
N#CC=1C=C (SC1N2C (=CC (C (=O) NC3=NC=4C=CC (OC) =CC4N3) =C2C) C) C
Molecular Formula
C21H19N5O2S
Molecular Weight
405.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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