JH-131e-153
JH-131e-153 is a DAG-lactone activator of the Munc13-1 C1 domain, with a selectivity profile favoring PKCα over Munc13-1 and PKCε. It serves as a key pharmacological tool for studying synaptic vesicle priming and neurotransmission in vitro, with research implications for neurodegenerative conditions.
Product Specifications
CAS Number
742104-91-2
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
C (OC (C (C) (C) C) =O) [C@]1 (CO) C\C (=C\CC (CC (C) C) CC (C) C) \C (=O) O1
Molecular Formula
C22H38O5
Molecular Weight
382.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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