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JH-131e-153

JH-131e-153 is a DAG-lactone activator of the Munc13-1 C1 domain, with a selectivity profile favoring PKCα over Munc13-1 and PKCε. It serves as a key pharmacological tool for studying synaptic vesicle priming and neurotransmission in vitro, with research implications for neurodegenerative conditions.

Product Specifications

CAS Number

742104-91-2

Field of Research

Epigenetics & Chromatin, Signal Transduction

Smiles

C (OC (C (C) (C) C) =O) [C@]1 (CO) C\C (=C\CC (CC (C) C) CC (C) C) \C (=O) O1

Molecular Formula

C22H38O5

Molecular Weight

382.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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