ICMT-IN-53
ICMT-IN-53 (compound 12) is a potent ICMT inhibitor with an IC50 of 0.96 μM, demonstrating good membrane permeability and antiproliferative activity in vitro against MDA-MB-231 and PC3 cancer cell lines. This small molecule is a valuable research tool for studying protein prenylation and oncology, particularly in Ras-driven cancer models.
Product Specifications
CAS Number
1443253-17-5
Field of Research
Cell Biology, Metabolism Research
Smiles
FC=1C=NC=CC1C2=CC=C3C (=C2) C (=CN3CCCCCCCC) CN (CC) CC
Molecular Formula
C26H36FN3
Molecular Weight
409.58
Storage Conditions
-20°C
Notes
For research use only.
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