ICMT-IN-25
ICMT-IN-25 (compound 37) is a highly potent and selective small molecule inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), with an IC50 of 25 nM. This tool compound is used in vitro and in vivo to investigate the role of ICMT in Ras localization, cancer biology, and prenylated protein function.
Product Specifications
CAS Number
1313602-83-3
Field of Research
Cell Biology, Metabolism Research
Smiles
ClC1=CC=CC (=C1) NCCC2 (C=3C=CC=CC3) CCOC (C) (C) C2
Molecular Formula
C21H26ClNO
Molecular Weight
343.89
Storage Conditions
-20°C
Notes
For research use only.
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