MDM2-IN-1
MDM2-IN-1 (Compound 30) is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans-configuration. MDM2-IN-1 can be used for the study of osteosarcoma[1].
Product Specifications
CAS Number
1410737-09-5
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdm2-in-1.html
Purity
98.02
Solubility
DMF : 10 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 22 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C([C@H](N1)[C@H](C2=CC=CC(Cl)=C2F)[C@]3(C(NC4=C3C=CC(Cl)=C4)=O)C51CCCCC5)O
Molecular Formula
C23H21Cl2FN2O3
Molecular Weight
463.33
References & Citations
[1]Aguilar A, et al. Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles. J Med Chem. 2014 Dec 26;57 (24) :10486-98.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
E-CL-R0374-01 24 Tests
Rat PDGF-BB (Platelet-Derived Growth Factor-BB) CLIA Kit
Sign In for Pricing
View Details E-CL-R0374-02 48 Tests
Rat PDGF-BB (Platelet-Derived Growth Factor-BB) CLIA Kit
Sign In for Pricing
View Details E-CL-R0374-03 96 Tests
Rat PDGF-BB (Platelet-Derived Growth Factor-BB) CLIA Kit
Sign In for Pricing
View Details 
BNC683551-100 1x 100 µL
Synaptophysin (Neuroendocrine Marker) (SYP/3551), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
LC422716 20 µg
TrkB (NTRK2) (NM_001018065) Human Over-expression Lysate
Sign In for Pricing
View Details