ICMT-IN-1
ICMT-IN-1 (compound 75) is a highly potent inhibitor of ICMT, exhibiting an IC50 of 0.0013 μM. It induces cytoplasmic retention of ICMT in HCT-116 cells and suppresses the growth of K-Ras and N-Ras-expressing cancer cell lines in vitro, making it a valuable tool for studying Ras-driven oncogenesis.
Product Specifications
CAS Number
1313603-22-3
Field of Research
Cell Biology, Metabolism Research
Smiles
O (C1=CC=CC (=C1) NCCC2 (C=3C=CC=CC3) CC (OC (C) (C) C2) (C) C) C
Molecular Formula
C24H33NO2
Molecular Weight
367.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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