Pregomisin
Pregomisin is a natural compound isolated from the fruits of Schizandra chinensis Baill. Pregomisin showed PAF antagonistic activity and the IC50 values were 48 μM[1].
Product Specifications
CAS Number
66280-26-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Platelet-activating Factor Receptor (PAFR)
Type
Natural Products
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pregomisin.html
Purity
99.87
Solubility
10 mM in DMSO
Smiles
C[C@@H](CC1=CC(O)=C(OC)C(OC)=C1)[C@H](C)CC2=CC(O)=C(OC)C(OC)=C2
Molecular Formula
C22H30O6
Molecular Weight
390.47
Precautions
H302, H315, H319, H335
References & Citations
[1]I S Lee, et al. Platelet-activating factor antagonistic activity and (13) C NMR assignment of pregomisin and chamigrenal fromSchisandra chinensis. Arch Pharm Res. 1997 Dec;20 (6) :633-6. |[2]Lee IS, et al. Platelet-activating factor antagonistic activity and (13) C NMR assignment of pregomisin and chamigrenal fromSchisandra chinensis. Arch Pharm Res. 1997;20 (6) :633-636.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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