Pregomisin

Pregomisin is a natural compound isolated from the fruits of Schizandra chinensis Baill. Pregomisin showed PAF antagonistic activity and the IC50 values were 48 μM[1].

Product Specifications

CAS Number

[66280-26-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Platelet-activating Factor Receptor (PAFR)

Type

Natural Products

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/pregomisin.html

Purity

99.87

Solubility

10 mM in DMSO

Smiles

C[C@@H](CC1=CC(O)=C(OC)C(OC)=C1)[C@H](C)CC2=CC(O)=C(OC)C(OC)=C2

Molecular Formula

C22H30O6

Molecular Weight

390.47

Precautions

H302, H315, H319, H335

References & Citations

[1]I S Lee, et al. Platelet-activating factor antagonistic activity and (13) C NMR assignment of pregomisin and chamigrenal fromSchisandra chinensis. Arch Pharm Res. 1997 Dec;20 (6) :633-6. |[2]Lee IS, et al. Platelet-activating factor antagonistic activity and (13) C NMR assignment of pregomisin and chamigrenal fromSchisandra chinensis. Arch Pharm Res. 1997;20 (6) :633-636.