HTH-02-006
HTH-02-006 is a potent NUAK2 inhibitor (IC50 = 126 nM) that suppresses YAP-driven proliferation and tumorigenesis. It reduces phospho-MYPT1 in HuCCT-1 cells and demonstrates in vivo efficacy against hepatomegaly and fibrosis, making it a valuable research tool for studying Hippo pathway-related cancers and fibrotic diseases.
Product Specifications
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
IC1=CN=C (NC2=CC=C (N3CCN (C) CC3) C=C2OC) N=C1OC4=CC (NC (CC) =O) =CC=C4
Molecular Formula
C25H29IN6O3
Molecular Weight
588.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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