CDK2-IN-20

CDK2-IN-20 (compound 3b) is a cyclin-dependent kinase 2 (CDK2) inhibitor exhibiting potent anti-proliferative activity against tumor cells, with IC50 values between 5.52 and 17.09 μM. In vitro studies using MCF-7 breast cancer cells demonstrate it induces S-phase cell cycle arrest and promotes apoptosis, supporting its utility in oncology and cell cycle research.