BMS-496
BMS-496 is a potent and selective dual inhibitor of diacylglycerol kinases alpha (DGKα) and zeta (DGKζ), with IC50 values of 90 nM and 6 nM, respectively. This small molecule is a valuable research tool for studying DGK signaling in immune cell function, T-cell activation, and cancer biology in both cellular and biochemical assays.
Product Specifications
CAS Number
2407854-31-1
Smiles
O=C1C (=C (C=2N=C (Br) C=CC2N1C) N3CCN (CC3) C (C4=CC=C (F) C=C4) C5=CC=C (F) C=C5) N (=O) =O
Molecular Formula
C26H22BrF2N5O3
Molecular Weight
570.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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