Suvorexant
A potent, CNS penetrant, orally available, dual orexin receptor antagonist with Ki of 0.55 and 0.35 nM for OX1R and OX2R, respectively; significantly and dose-dependently reduces locomotor activity and promotes sleep in rats.Sleep Disorder Launched.
Product Specifications
CAS Number
1030377-33-3
Product Name Alternative
MK-4305
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (N1CCN (C2=NC3=CC (Cl) =CC=C3O2) CC[C@H]1C) C4=CC (C) =CC=C4N5N=CC=N5
Molecular Formula
C23H23ClN6O2
Molecular Weight
450.92
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(R) - (4- (5-chlorobenzo[d]oxazol-2-yl) -7-methyl-1,4-diazepan-1-yl) (5-methyl-2- (2H-1,2,3-triazol-2-yl) phenyl) methanone
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