AZD 4320

AZD4320 is a BH3 mimetic and dual Bcl-2/Bcl-XL inhibitor with IC50 of 24 days) tumor regressions in a mouse RS4;11 acute lymphocytic leukemia xenograft model (20 mg/kg, i.v.) .

Product Specifications

CAS Number

1357576-48-7

Product Name Alternative

AZD4320

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 100 mg/mL (105.76 mM)

Smiles

O=C (NS (=O) (C1=CC=C (N[C@H] (CCN (CCO) C) CSC2=CC=CC=C2) C (S (=O) (C (F) (F) F) =O) =C1) =O) C3=CC=C (N4CCC ([C@H] (C5=CC=CC=C5C6=CC=C (Cl) C=C6) O) CC4) C=C3

Molecular Formula

C45H48ClF3N4O7S3

Molecular Weight

945.525

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4- (4- ((R) - (4'-chloro-[1,1'-biphenyl]-2-yl) (hydroxy) methyl) piperidin-1-yl) -N- ((4- (((R) -4- ((2-hydroxyethyl) (methyl) amino) -1- (phenylthio) butan-2-yl) amino) -3- ((trifluoromethyl) sulfonyl) phenyl) sulfonyl) benzamide