GEM–IB
The GEM-IB conjugate, linking gemcitabine-5'-phosphate to ibandronate, demonstrates single-agent and docetaxel-synergistic activity in osteosarcoma research. It reduces tumor growth, preserves bone integrity, and improves survival in murine models, supporting its study in bone-targeted oncology and preclinical therapeutic experiments.
Product Specifications
CAS Number
2866211-93-8
Smiles
FC1 (F) [C@@H] (O[C@H] (COP (OP (C (CCN (CCCCC) C) (P (=O) (O) O) O) (=O) O) (=O) O) [C@H]1O) N2C (=O) N=C (N) C=C2
Molecular Formula
C18H33F2N4O13P3
Molecular Weight
644.39
Storage Conditions
-20°C
Notes
For research use only.
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