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FBnG- (Cys-acetamide) -CH2-PEG3-CH2-CH2-CH2-NH2

This product is the linker component of AUTAC4, connecting a p-fluorobenzylguanine (FBnG) unit to a phenylindole moiety. It facilitates K63-linked polyubiquitination, leading to targeted mitophagy in cellular models like HeLa cells, and is a tool for studying mitochondrial degradation pathways in vitro.

Product Specifications

CAS Number

2241669-84-9

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Smiles

C (N1C2=C (N=C1SC[C@@H] (C (NCCCOCCOCCOCCCN) =O) NC (C) =O) C (=O) N=C (N) N2) C3=CC=C (F) C=C3

Molecular Formula

C27H39FN8O6S

Molecular Weight

622.71

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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