FBnG- (Cys-acetamide) -CH2-PEG3-CH2-CH2-CH2-NH2
This product is the linker component of AUTAC4, connecting a p-fluorobenzylguanine (FBnG) unit to a phenylindole moiety. It facilitates K63-linked polyubiquitination, leading to targeted mitophagy in cellular models like HeLa cells, and is a tool for studying mitochondrial degradation pathways in vitro.
Product Specifications
CAS Number
2241669-84-9
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
C (N1C2=C (N=C1SC[C@@H] (C (NCCCOCCOCCOCCCN) =O) NC (C) =O) C (=O) N=C (N) N2) C3=CC=C (F) C=C3
Molecular Formula
C27H39FN8O6S
Molecular Weight
622.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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