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EGFR/HER2/DHFR-IN-3

EGFR/HER2/DHFR-IN-3 is a potent dual inhibitor of EGFR (IC50=0.138 μM) and HER2 (IC50=0.092 μM), with additional DHFR inhibition (IC50=0.193 μM) . It induces S-phase cell cycle arrest and apoptosis in MCF7 breast cancer cells, supporting its application in oncology research and mechanistic studies.

Product Specifications

Field of Research

Cardiovascular Research, Cell Biology, Metabolism Research, Metabolism Research; Cell Biology, Molecular Biology, Signal Transduction

Storage Conditions

-20°C

Notes

For research use only.

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