Desmethyl Vc-seco-DUBA

Desmethyl Vc-seco-DUBA is a chemical payload-linker conjugate designed for constructing antibody-drug conjugates (ADCs) . It incorporates a protease-cleavable linker attached to the DNA-alkylating agent DUBA, enabling the targeted delivery of cytotoxic payloads in ADC development for oncology research, applicable in both in vitro and in vivo experimental models.