DA-PROTAC
DA-PROTAC is a bifunctional molecule that induces the degradation of the copper chaperones Atox1 and CCS by recruiting an E3 ligase, leading to their ubiquitination and proteasomal clearance. It is a research tool used in cellular models to study copper homeostasis and its role in diseases such as triple-negative breast cancer.
Product Specifications
CAS Number
2488660-12-2
Field of Research
Pharmacology & Drug Discovery
Smiles
N (C (COCCCOCC (NC (C (=O) N1[C@H] (C (NCC2=CC=C (C=C2) C3=C (C) N=CS3) =O) C[C@@H] (O) C1) C (C) (C) C) =O) =O) C=4C5=C (SC4C (NC6=C (Br) C=C (F) C=C6F) =O) N=C7C (=C5) CCC7
Molecular Formula
C46H50BrF2N7O8S2
Molecular Weight
1010.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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