Amidate-VC-PAB-MMAF
Amidate-VC-PAB-MMAF is a cleavable linker-payload conjugate used in antibody-drug conjugate (ADC) synthesis to minimize off-target cytotoxicity. It integrates a VC-PAB linker with the tubulin inhibitor MMAF for targeted cancer therapy research, supporting in vitro and in vivo preclinical studies for controlled drug release.
Product Specifications
CAS Number
2202782-90-7
Smiles
[C@H] ([C@H] (C (N[C@@H] (CC1=CC=CC=C1) C (O) =O) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC3=CC=C (NC ([C@@H] (NC ([C@@H] (NC (=O) C4=CC=C (NP (OCC) (C#C) =O) C=C4) [C@@H] (C) C) =O) CCCNC (N) =O) =O) C=C3) =O) C) C (C) C) =O) [C@@H] (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C69H102N11O16P
Molecular Weight
1372.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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